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New RFA - Genesis Mission: Transforming Science and Energy with AI

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On March 17, the U.S. Department of Energy (DOE) announced interest in receiving applications from interdisciplinary teams addressing the Genesis Mission National Science and Technology Challenges to accelerate scientific discovery and R&D workflow using novel AI models and frameworks.

By achieving AI advantage, these teams will advance the DOE's mission and ensure America’s security and prosperity by addressing energy, environmental, and nuclear challenges through science and technology. Funding Details

  • DOE expects to make multiple awards
  • Total available program funding: $293,760,000
  • Submission Deadline for FY26 Phase I Applications: April 28, 2026
  • Submission Deadline for FY26 Phase II Letters of Intent: April 28, 2026

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Teams are encouraged to leverage the extensive scientific and data resources of the DOE, the National Laboratories, U.S. industry, and academia. Any resulting AI models, workflows, and data, will be integrated into the larger Genesis Mission capabilities.

For questions about this opportunity, contact GenesisMissionNOFO@science.doe.gov.

To support formation of strategic partnerships for Genesis Mission opportunities, the Genesis Mission Consortium will launch the Partnership Exchange on Thursday, March 19 at 4:00 PM ET. Learn more about the Partnership Exchange at the link below.

Partnership Exchange Information>>

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