SOUTH CAROLINA: Clemson receives part of $15.8M in awards from NIIMBL
Clemson University is one of a team of institutions who have received one of 14 new projects in technology and workforce development awarded by the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL). NIIMBL awarded a total of approximately $15.8 million in planned project activities through the Institute’s Project Call 5.2 that will help to address key opportunities for innovation in the biopharmaceutical industry.
NIIMBL is a public-private partnership whose mission is to accelerate biopharmaceutical innovation, support the development of standards that enable more efficient and rapid manufacturing capabilities, and educate and train a world-leading biopharmaceutical manufacturing workforce, fundamentally advancing US competitiveness in this industry. NIIMBL is part of Manufacturing USA®, a diverse network of federally-sponsored manufacturing innovation institutes, and is funded through a cooperative agreement with the National Institute of Standards and Technology (NIST) in the US Department of Commerce with significant additional support from its members.
Project: Advanced Bioprocessing Sensor and Analytical Technologies for Induced Pluripotent Stem Cell Culture Online Monitoring and Automation
Lead: Northeastern University
Participant(s): Agilent, CLEMSON UNIVERSITY, MilliporeSigma/EMD Serono, Physical Sciences Inc., University of Massachusetts System
The goal of this project is to improve the production of induced pluripotent stem cells (iPSCs) by developing a robust online sensor and building a knowledge graph hybrid model-based machine learning (KG-ML) algorithm to advance the scientific understanding of metabolism by correlating online sensing and the intracellular metabolic state of the culture process. The technology and monitoring will safeguard that the culture follows the expected trajectory for successful growth and expansion.